Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease

Vascular endothelial cells play an important role in maintaining brain health, but their contribution to Alzheimer's disease (AD) is obscured by limited understanding of the cellular heterogeneity in normal aged brain and in disease. To address this, we performed single nucleus RNAseq on tissue...

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Detalles Bibliográficos
Autores principales: Bryant, Annie, Li, Zhaozhi, Jayakumar, Rojashree, Serrano-Pozo, Alberto, Woost, Benjamin, Hu, Miwei, Woodbury, Maya E., Wachter, Astrid, Lin, Gen, Kwon, Taekyung, Talanian, Robert V., Biber, Knut, Karran, Eric H., Hyman, Bradley T., Das, Sudeshna, Bennett, Rachel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278684/
https://www.ncbi.nlm.nih.gov/pubmed/37208174
http://dx.doi.org/10.1523/JNEUROSCI.0237-23.2023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278684/
https://www.ncbi.nlm.nih.gov/pubmed/37208174
http://dx.doi.org/10.1523/JNEUROSCI.0237-23.2023

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