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Omarigliptin Protects the Integrity of the Blood–Brain Barrier After Intracerebral Hemorrhage in Mice

PURPOSE: Intracerebral hemorrhage (ICH) is a fatal disease without effective treatment. The damage of the blood–brain barrier (BBB) is a key cause of brain edema and herniation after ICH. Omarigliptin (also known as MK3102) is a potent antidiabetic that inhibits dipeptidyl peptidase (DPP4); the latt...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Liu, Yang, Zhang, Xiangyu, Yong, V Wee, Xue, Mengzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278948/
https://www.ncbi.nlm.nih.gov/pubmed/37342770
http://dx.doi.org/10.2147/JIR.S411017