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Cell metabolism-based optimization strategy of CAR-T cell function in cancer therapy

Adoptive cell therapy (ACT) using chimeric antigen receptor (CAR)-modified T cells has revolutionized the field of immune-oncology, showing remarkable efficacy against hematological malignancies. However, its success in solid tumors is limited by factors such as easy recurrence and poor efficacy. Th...

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Detalles Bibliográficos
Autores principales: Li, Wenshuai, Pan, Xuanxuan, Chen, Lirong, Cui, Haoshu, Mo, Shaocong, Pan, Yida, Shen, Yuru, Shi, Menglin, Wu, Jianlin, Luo, Feifei, Liu, Jie, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278966/
https://www.ncbi.nlm.nih.gov/pubmed/37342333
http://dx.doi.org/10.3389/fimmu.2023.1186383