Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling

In tissue development and homeostasis, transforming growth factor (TGF)-β signaling is finely coordinated by latent forms and matrix sequestration. Optogenetics can offer precise and dynamic control of cell signaling. We report the development of an optogenetic human induced pluripotent stem cell sy...

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Detalles Bibliográficos
Autores principales: Wu, Josephine Y., Yeager, Keith, Tavakol, Daniel Naveed, Morsink, Margaretha, Wang, Bryan, Soni, Rajesh Kumar, Hung, Clark T., Vunjak-Novakovic, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278972/
https://www.ncbi.nlm.nih.gov/pubmed/37178118
http://dx.doi.org/10.1016/j.celrep.2023.112509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278972/
https://www.ncbi.nlm.nih.gov/pubmed/37178118
http://dx.doi.org/10.1016/j.celrep.2023.112509

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