Post-injury Inhibition of Endothelin-1 Dependent Renal Vasoregulation Mitigates Rhabdomyolysis-Induced Acute Kidney Injury

In patients with rhabdomyolysis, the overwhelming release of myoglobin into the circulation is the primary cause of kidney injury. Myoglobin causes direct kidney injury as well as severe renal vasoconstriction. An increase in renal vascular resistance (RVR) results in renal blood flow (RBF) and glom...

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Detalles Bibliográficos
Autores principales: Afolabi, Jeremiah M, Kanthakumar, Praghalathan, Williams, Jada D, Kumar, Ravi, Soni, Hitesh, Adebiyi, Adebowale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278989/
https://www.ncbi.nlm.nih.gov/pubmed/37342410
http://dx.doi.org/10.1093/function/zqad022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278989/
https://www.ncbi.nlm.nih.gov/pubmed/37342410
http://dx.doi.org/10.1093/function/zqad022

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