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Molecular basis of the TRAP complex function in ER protein biogenesis

The translocon-associated protein (TRAP) complex resides in the endoplasmic reticulum (ER) membrane and interacts with the Sec translocon and the ribosome to facilitate biogenesis of secretory and membrane proteins. TRAP plays a key role in the secretion of many hormones, including insulin. Here we...

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Detalles Bibliográficos
Autores principales: Jaskolowski, Mateusz, Jomaa, Ahmad, Gamerdinger, Martin, Shrestha, Sandeep, Leibundgut, Marc, Deuerling, Elke, Ban, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279528/
https://www.ncbi.nlm.nih.gov/pubmed/37170030
http://dx.doi.org/10.1038/s41594-023-00990-0