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WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines

Collectively, the MYC family of oncoprotein transcription factors is overexpressed in more than half of all malignancies. The ability of MYC proteins to access chromatin is fundamental to their role in promoting oncogenic gene expression programs in cancer and this function depends on MYC–cofactor i...

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Detalles Bibliográficos
Autores principales: Bumpous, Leigh A., Moe, Kylie C., Wang, Jing, Carver, Logan A., Williams, Alexandria G., Romer, Alexander S., Scobee, Jesse D., Maxwell, Jack N., Jones, Cheyenne A., Chung, Dai H., Tansey, William P., Liu, Qi, Weissmiller, April M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279693/
https://www.ncbi.nlm.nih.gov/pubmed/37336886
http://dx.doi.org/10.1038/s41389-023-00477-z