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WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines
Collectively, the MYC family of oncoprotein transcription factors is overexpressed in more than half of all malignancies. The ability of MYC proteins to access chromatin is fundamental to their role in promoting oncogenic gene expression programs in cancer and this function depends on MYC–cofactor i...
Autores principales: | Bumpous, Leigh A., Moe, Kylie C., Wang, Jing, Carver, Logan A., Williams, Alexandria G., Romer, Alexander S., Scobee, Jesse D., Maxwell, Jack N., Jones, Cheyenne A., Chung, Dai H., Tansey, William P., Liu, Qi, Weissmiller, April M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279693/ https://www.ncbi.nlm.nih.gov/pubmed/37336886 http://dx.doi.org/10.1038/s41389-023-00477-z |
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