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Safety and immunogenicity of a phase 1/2 randomized clinical trial of a quadrivalent, mRNA-based seasonal influenza vaccine (mRNA-1010) in healthy adults: interim analysis

Despite vaccine availability, influenza remains a substantial global public health concern. Here, we report interim findings on the primary and secondary objectives of the safety, reactogenicity, and humoral immunogenicity of a quadrivalent messenger RNA (mRNA) vaccine against seasonal influenza, mR...

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Detalles Bibliográficos
Autores principales: Lee, Ivan T., Nachbagauer, Raffael, Ensz, David, Schwartz, Howard, Carmona, Lizbeth, Schaefers, Kristi, Avanesov, Andrei, Stadlbauer, Daniel, Henry, Carole, Chen, Ren, Huang, Wenmei, Schrempp, Daniela Ramirez, Ananworanich, Jintanat, Paris, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279702/
https://www.ncbi.nlm.nih.gov/pubmed/37336877
http://dx.doi.org/10.1038/s41467-023-39376-7