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Genomic analysis of plasma circulating tumor DNA in patients with heavily pretreated HER2 + metastatic breast cancer

We explored accumulated genomic alterations in patients with heavily treated HER2 + metastatic breast cancer enrolled in the KCSG BR18-14/KM10B trial. Targeted sequencing was performed with circulating tumor DNAs (ctDNAs) collected before the treatment of 92 patients. ctDNAs collected at the time of...

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Detalles Bibliográficos
Autores principales: Lee, Kyoungmin, Lee, Jongwon, Choi, Jungmin, Sim, Sung Hoon, Kim, Jeong Eun, Kim, Min Hwan, Park, Yeon Hee, Kim, Jee Hyun, Koh, Su-Jin, Park, Kyong Hwa, Kang, Myoung Joo, Ahn, Mi Sun, Lee, Kyoung Eun, Kim, Hee-Jun, Ahn, Hee Kyung, Kim, Han Jo, Park, Keon Uk, Park, In Hae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279711/
https://www.ncbi.nlm.nih.gov/pubmed/37336919
http://dx.doi.org/10.1038/s41598-023-35925-8