Activating hidden signals by mimicking cryptic sites in a synthetic extracellular matrix

Cryptic sites are short signaling peptides buried within the native extracellular matrix (ECM). Enzymatic cleavage of an ECM protein reveals these hidden peptide sequences, which interact with surface receptors to control cell behavior. Materials that mimic this dynamic interplay between cells and t...

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Detalles Bibliográficos
Autores principales: Zhu, Yumeng, Shmidov, Yulia, Harris, Elizabeth A., Theus, Michelle H., Bitton, Ronit, Matson, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279755/
https://www.ncbi.nlm.nih.gov/pubmed/37336876
http://dx.doi.org/10.1038/s41467-023-39349-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279755/
https://www.ncbi.nlm.nih.gov/pubmed/37336876
http://dx.doi.org/10.1038/s41467-023-39349-w

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