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Activating hidden signals by mimicking cryptic sites in a synthetic extracellular matrix
Cryptic sites are short signaling peptides buried within the native extracellular matrix (ECM). Enzymatic cleavage of an ECM protein reveals these hidden peptide sequences, which interact with surface receptors to control cell behavior. Materials that mimic this dynamic interplay between cells and t...
Autores principales: | Zhu, Yumeng, Shmidov, Yulia, Harris, Elizabeth A., Theus, Michelle H., Bitton, Ronit, Matson, John B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279755/ https://www.ncbi.nlm.nih.gov/pubmed/37336876 http://dx.doi.org/10.1038/s41467-023-39349-w |
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