Tuberous Sclerosis Complex cell‐derived EVs have an altered protein cargo capable of regulating their microenvironment and have potential as disease biomarkers

Hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) is a feature of many solid tumours and is a key pathogenic driver in the inherited condition Tuberous Sclerosis Complex (TSC). Modulation of the tumour microenvironment by extracellular vesicles (EVs) is known to facilitate the de...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhaoighill, Muireann Ní, Falcón‐Pérez, Juan M., Royo, Félix, Tee, Andrew R., Webber, Jason P., Dunlop, Elaine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279809/
https://www.ncbi.nlm.nih.gov/pubmed/37337371
http://dx.doi.org/10.1002/jev2.12336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279809/
https://www.ncbi.nlm.nih.gov/pubmed/37337371
http://dx.doi.org/10.1002/jev2.12336

Ejemplares similares