Tuberous Sclerosis Complex cell‐derived EVs have an altered protein cargo capable of regulating their microenvironment and have potential as disease biomarkers

Hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) is a feature of many solid tumours and is a key pathogenic driver in the inherited condition Tuberous Sclerosis Complex (TSC). Modulation of the tumour microenvironment by extracellular vesicles (EVs) is known to facilitate the de...

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Detalles Bibliográficos
Autores principales: Bhaoighill, Muireann Ní, Falcón‐Pérez, Juan M., Royo, Félix, Tee, Andrew R., Webber, Jason P., Dunlop, Elaine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279809/
https://www.ncbi.nlm.nih.gov/pubmed/37337371
http://dx.doi.org/10.1002/jev2.12336

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