AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity

The human AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 are multipass plasma membrane proteins that protect cells against membrane rigidification. However, how AdipoR2 promotes membrane fluidity mechanistically is not clear. Using 13C-labeled fatty acids, we show that AdipoR2 can promote the...

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Detalles Bibliográficos
Autores principales: Ruiz, Mario, Devkota, Ranjan, Kaper, Delaney, Ruhanen, Hanna, Busayavalasa, Kiran, Radović, Uroš, Henricsson, Marcus, Käkelä, Reijo, Borén, Jan, Pilon, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Lipids
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279913/
https://www.ncbi.nlm.nih.gov/pubmed/37164154
http://dx.doi.org/10.1016/j.jbc.2023.104799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279913/
https://www.ncbi.nlm.nih.gov/pubmed/37164154
http://dx.doi.org/10.1016/j.jbc.2023.104799

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