Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P(2) hydrolysis in the plasma membrane

T-cell acute lymphoblastic leukemia (T-ALL) is one of the deadliest and most aggressive hematological malignancies, but its pathological mechanism in controlling cell survival is not fully understood. Oculocerebrorenal syndrome of Lowe is a rare X-linked recessive disorder characterized by cataracts...

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Detalles Bibliográficos
Autores principales: Chen, Huanzhao, Lu, Chen, Tan, Yuhui, Weber-Boyvat, Marion, Zheng, Jie, Xu, Mengyang, Xiao, Jie, Liu, Shuang, Tang, Zhiquan, Lai, Chaofeng, Li, Mingchuan, Olkkonen, Vesa M., Yan, Daoguang, Zhong, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279916/
https://www.ncbi.nlm.nih.gov/pubmed/37172724
http://dx.doi.org/10.1016/j.jbc.2023.104812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279916/
https://www.ncbi.nlm.nih.gov/pubmed/37172724
http://dx.doi.org/10.1016/j.jbc.2023.104812

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