Cargando…

Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P(2) hydrolysis in the plasma membrane

T-cell acute lymphoblastic leukemia (T-ALL) is one of the deadliest and most aggressive hematological malignancies, but its pathological mechanism in controlling cell survival is not fully understood. Oculocerebrorenal syndrome of Lowe is a rare X-linked recessive disorder characterized by cataracts...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Huanzhao, Lu, Chen, Tan, Yuhui, Weber-Boyvat, Marion, Zheng, Jie, Xu, Mengyang, Xiao, Jie, Liu, Shuang, Tang, Zhiquan, Lai, Chaofeng, Li, Mingchuan, Olkkonen, Vesa M., Yan, Daoguang, Zhong, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279916/ https://www.ncbi.nlm.nih.gov/pubmed/37172724 http://dx.doi.org/10.1016/j.jbc.2023.104812

Ejemplares similares

Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe
por: Luo, Na, et al.
Publicado: (2013)

Novel pathogenic OCRL mutations and genotype–phenotype analysis of Chinese children affected by oculocerebrorenal syndrome: two cases and a literature review
por: Zhang, Yu, et al.
Publicado: (2021)

An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis
por: Zhong, Wenbin, et al.
Publicado: (2022)

Identification and functional analysis of a novel oculocerebrorenal syndrome of Lowe (OCRL) gene variant in two pedigrees with varying phenotypes including isolated congenital cataract
por: Shalaby, Ahmed K., et al.
Publicado: (2018)

The oculocerebrorenal syndrome of Lowe: an update
por: Bökenkamp, Arend, et al.
Publicado: (2016)

Ocular Pathology of Oculocerebrorenal Syndrome of Lowe: Novel Mutations and Genotype-Phenotype Analysis
por: Song, Emilie, et al.
Publicado: (2017)

The unexpected role of Drosophila OCRL during cytokinesis
por: Ben El Kadhi, Khaled, et al.
Publicado: (2012)

A role for OCRL in glomerular function and disease
por: Preston, Rebecca, et al.
Publicado: (2019)

ORP/Osh mediate cross-talk between ER-plasma membrane contact site components and plasma membrane SNAREs
por: Weber-Boyvat, Marion, et al.
Publicado: (2020)

Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev‐erbα Knock‐ Down
por: Ma, Hongling, et al.
Publicado: (2013)

ORP4L is a prerequisite for the induction of T-cell leukemogenesis associated with human T-cell leukemia virus 1
por: Zhong, Wenbin, et al.
Publicado: (2022)

Genotype-Phenotype Correlation Reanalysis in 83 Chinese Cases with OCRL Mutations
por: Zhang, Lingxia, et al.
Publicado: (2022)

Recognition of the F&H motif by the Lowe Syndrome protein OCRL
por: Pirruccello, Michelle, et al.
Publicado: (2011)

The Cellular and Physiological Functions of the Lowe Syndrome Protein OCRL1
por: Mehta, Zenobia B, et al.
Publicado: (2014)

Assessment of endocytic traffic and Ocrl function in the developing zebrafish neuroepithelium
por: Williams, Daniel M., et al.
Publicado: (2022)

OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62
por: Zhou, Tianhong, et al.
Publicado: (2011)

The Lowe syndrome protein OCRL1 is involved in primary cilia assembly
por: Hernandez, V, et al.
Publicado: (2012)

dOCRL maintains immune cell quiescence by regulating endosomal traffic
por: Del Signore, Steven J., et al.
Publicado: (2017)

Lowe Syndrome Protein OCRL1 Supports Maturation of Polarized Epithelial Cells
por: Grieve, Adam G., et al.
Publicado: (2011)

A Novel Pathogenic DNA Variation in the OCRL1 Gene in Lowe Syndrome
por: Şimşek, Enver, et al.
Publicado: (2011)

OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome
por: Luo, Na, et al.
Publicado: (2012)

The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule
por: Oltrabella, Francesca, et al.
Publicado: (2015)

SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase
por: Choi, Won Young, et al.
Publicado: (2021)

X-inactivation analysis of embryonic lethality in Ocrl(wt/−);Inpp5b(−/−) mice
por: Bernard, David J., et al.
Publicado: (2010)

Splicing Analysis of Exonic OCRL Mutations Causing Lowe Syndrome or Dent-2 Disease
por: Suarez-Artiles, Lorena, et al.
Publicado: (2018)

ORP2 couples LDL‐cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P(2) exchange
por: Takahashi, Kohta, et al.
Publicado: (2021)

Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL
por: De Leo, Maria Giovanna, et al.
Publicado: (2016)

Lowe syndrome–linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum
por: Luscher, Alexandre, et al.
Publicado: (2019)

Understanding Anthracycline Cardiotoxicity From Mitochondrial Aspect
por: Huang, Junqi, et al.
Publicado: (2022)

Whole‐genome sequencing revealed an interstitial deletion encompassing OCRL and SMARCA1 gene in a patient with Lowe syndrome
por: Zheng, Bixia, et al.
Publicado: (2019)

OSBP-Related Protein Family in Lipid Transport Over Membrane Contact Sites
por: Olkkonen, Vesa M.
Publicado: (2015)

OSBP-Related Proteins: Liganding by Glycerophospholipids Opens New Insight into Their Function
por: Olkkonen, Vesa M.
Publicado: (2013)

OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates
por: Billcliff, Peter G., et al.
Publicado: (2016)

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells
por: Nández, Ramiro, et al.
Publicado: (2014)

Digenic mutations of human OCRL paralogs in Dent’s disease type 2 associated with Chiari I malformation
por: Duran, Daniel, et al.
Publicado: (2016)

OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease
por: Festa, Beatrice Paola, et al.
Publicado: (2019)

ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival
por: Zhong, Wenbin, et al.
Publicado: (2016)

Fluorouracil Selectively Enriches Stem-like Leukemic Cells in a Leukemic Cell Line
por: Zhang, Ling, et al.
Publicado: (2010)

The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway
por: Noakes, Christopher J., et al.
Publicado: (2011)

Dent-2 disease with a Bartter-like phenotype caused by the Asp631Glu mutation in the OCRL gene
por: Drosataki, Eleni, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_155ku5h3q61asiju27f8i1mq6m