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Noncovalent interactions that tune the reactivities of the flavins in bifurcating electron transferring flavoprotein

Bifurcating electron transferring flavoproteins (Bf-ETFs) tune chemically identical flavins to two contrasting roles. To understand how, we used hybrid quantum mechanical molecular mechanical calculations to characterize noncovalent interactions applied to each flavin by the protein. Our computation...

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Detalles Bibliográficos
Autores principales: González-Viegas, María, Kar, Rajiv K., Miller, Anne-Frances, Mroginski, Maria-Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279923/
https://www.ncbi.nlm.nih.gov/pubmed/37119850
http://dx.doi.org/10.1016/j.jbc.2023.104762