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CD24-Fc suppression of immune related adverse events in a therapeutic cancer vaccine model of murine neuroblastoma

INTRODUCTION: The combination of Myc-suppressed whole tumor cells with checkpoint inhibitors targeting CTLA-4 and PD-L1 generates a potent therapeutic cancer vaccine in a mouse neuroblastoma model. As immunotherapies translate from pre-clinical to clinical trials, the potential immune-related advers...

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Detalles Bibliográficos
Autores principales: Wu, Xiaofang, Srinivasan, Priya, Basu, Mousumi, Zimmerman, Talia, Li, Samuel, Wang, Yin, Zheng, Pan, Liu, Yang, Sandler, Anthony David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279976/
https://www.ncbi.nlm.nih.gov/pubmed/37346042
http://dx.doi.org/10.3389/fimmu.2023.1176370