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Datumetine Preferentially Upregulates N-methyl-D-aspartate Receptor Signalling Pathways in Different Brain Regions of Mice

INTRODUCTION: We previously reported that datumetine possesses binding affinity with N-methyl-D-aspartate receptor (NMDAR) and that 14-day exposure to datumetine altered NMDAR signaling by mimicking glutamate toxicity. Here, we investigated the potential neuroprotective effect of a single shot of a...

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Detalles Bibliográficos
Autores principales: Ishola, Azeez Olakunle, Adetunji, Adedeji Enitan, Abanum, Isaac Chukwunwike, Adeyemi, Adesola Akorede, Faleye, Caleb Kenechukwu, Martins, Jane Babale, Ogbe, Nnenna Chimdalu, Ogundipe, Toluwalase Cherish, Okewulonu, Karen Ezichi, Okon, Umo Emmanuel, Ovbude, Deborah Irenoise, Akele, Richard Yomi, Omotade, Naeemat Tolulope, Ajao, Moyosore Salihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10279986/
https://www.ncbi.nlm.nih.gov/pubmed/37346877
http://dx.doi.org/10.32598/bcn.2021.3397.1