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Synthesis, characterization and biological evaluation of pyrazole-based benzene sulfonamides as inhibitors of human carbonic anhydrase II, IX and XII

The aberrant level of the carbonic anhydrase isozymes is linked with various disorders which include glaucoma, epilepsy, altitude sickness and obesity. In the present study, a series of the pyrazole-based benzene sulfonamides derivatives (4a–4l) were designed, synthesized and evaluated as the inhibi...

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Detalles Bibliográficos
Autores principales: Hussain, Tajamul, Ullah, Saif, Alrokayan, Salman, Alamery, Salman, Mohammed, Arif Ahmed, Ejaz, Syeda Abida, Aziz, Mubashir, Iqbal, Jamshed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280043/
https://www.ncbi.nlm.nih.gov/pubmed/37346960
http://dx.doi.org/10.1039/d3ra03276k