Asymmetric tandem conjugate addition and reaction with carbocations on acylimidazole Michael acceptors

We present here a stereoselective tandem reaction based on the asymmetric conjugate addition of dialkylzinc reagents to unsaturated acylimidazoles followed by trapping of the intermediate zinc enolate with carbocations. The use of a chiral NHC ligand provides chiral zinc enolates in high enantiomeri...

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Detalles Bibliográficos
Autores principales: Mudráková, Brigita, Marcia de Figueiredo, Renata, Campagne, Jean-Marc, Šebesta, Radovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280057/
https://www.ncbi.nlm.nih.gov/pubmed/37346500
http://dx.doi.org/10.3762/bjoc.19.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280057/
https://www.ncbi.nlm.nih.gov/pubmed/37346500
http://dx.doi.org/10.3762/bjoc.19.65

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