MutSα and MutSβ as size-dependent cellular determinants for prime editing in human embryonic stem cells

Precise genome editing in human pluripotent stem cells (hPSCs) has potential applications in isogenic disease modeling and ex vivo stem cell therapy, necessitating diverse genome editing tools. However, unlike differentiated somatic cells, hPSCs have unique cellular properties that maintain genome i...

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Detalles Bibliográficos
Autores principales: Park, Ju-Chan, Kim, Yun-Jeong, Han, Jun Hee, Kim, Dayeon, Park, Mihn Jeong, Kim, Jumee, Jang, Hyeon-Ki, Bae, Sangsu, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280094/
https://www.ncbi.nlm.nih.gov/pubmed/37346976
http://dx.doi.org/10.1016/j.omtn.2023.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280094/
https://www.ncbi.nlm.nih.gov/pubmed/37346976
http://dx.doi.org/10.1016/j.omtn.2023.05.015

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