Liver lobe-specific hydrodynamic gene delivery to baboons: A preclinical trial for hemophilia gene therapy

Hydrodynamics-based gene transfer has been successfully employed for in vivo gene delivery to the liver of small animals by tail vein injection and of large animals using a computer-assisted and image-guided protocol. In an effort to develop a hydrodynamic gene delivery procedure clinically applicab...

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Detalles Bibliográficos
Autores principales: Kamimura, Kenya, Kanefuji, Tsutomu, Suda, Takeshi, Yokoo, Takeshi, Zhang, Guisheng, Aoyagi, Yutaka, Liu, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280096/
https://www.ncbi.nlm.nih.gov/pubmed/37346981
http://dx.doi.org/10.1016/j.omtn.2023.05.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280096/
https://www.ncbi.nlm.nih.gov/pubmed/37346981
http://dx.doi.org/10.1016/j.omtn.2023.05.018

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