New cyclic glycolipids from Silene succulenta promote in vitro MCF-7 breast carcinoma cell apoptosis by cell cycle arrest and in silico mitotic Mps1/TTK inhibition

In vitro anticancer screening of Silene succulenta Forssk. aerial parts (Caryophyllaceae) showed that the n-hexane fraction was a highly effective fraction against breast carcinoma cell lines (MCF-7) with IC(50) = 15.5 μg mL(−1). The bioactive-guided approach led to the isolation of two new cyclic g...

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Detalles Bibliográficos
Autores principales: Badawy, Sarah A., Hassan, Ahmed R., Elkousy, Rawah H., Abu El wafa, Salwa A., Mohammad, Abd-El salam I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280128/
https://www.ncbi.nlm.nih.gov/pubmed/37346953
http://dx.doi.org/10.1039/d3ra01793a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280128/
https://www.ncbi.nlm.nih.gov/pubmed/37346953
http://dx.doi.org/10.1039/d3ra01793a

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