Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition

New 2-oxo-chromene-7-oxymethylene acetohydrazide derivatives 4a–d were designed and synthesized with a variety of bioactive chemical fragments. The newly synthesized compounds were evaluated as acetylcholinesterase (AChE) inhibitors and antioxidant agents in comparison to donepezil and ascorbic acid...

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Detalles Bibliográficos
Autores principales: Kamel, Nahla N., Aly, Hanan F., Fouad, Ghadha I., Abd El-Karim, Somaia S., Anwar, Manal M., Syam, Yasmin M., Elseginy, Samia A., Ahmed, Kawkab A., Booles, Hoda F., Shalaby, Mohamed B., Khalil, Wagdy K. B., Sandhir, Rajat, Deshwal, Sonam, Rizk, Maha Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280131/
https://www.ncbi.nlm.nih.gov/pubmed/37346948
http://dx.doi.org/10.1039/d3ra02344c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280131/
https://www.ncbi.nlm.nih.gov/pubmed/37346948
http://dx.doi.org/10.1039/d3ra02344c

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