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A chemically defined system supports two distinct types of stem cell from a single blastocyst and their self‐assembly to generate blastoid

The pluripotent stem cells exist in a narrow window during early development and its derivation depends on intrinsic and extrinsic growth signalling in vitro. It has remained challenging to derive two or three distinct cell lines that are representative of blastocyst‐stage lineages from one preimpla...

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Detalles Bibliográficos
Autores principales: Wu, Baojiang, Yang, Zhiqing, Liu, Yijie, Li, Jianwen, Chen, Chen, Li, Xihe, Bao, Siqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280139/
https://www.ncbi.nlm.nih.gov/pubmed/36593753
http://dx.doi.org/10.1111/cpr.13396