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Not Quite Lost in Translation: Mistranslation Alters Adaptive Landscape Topography and the Dynamics of Evolution

Mistranslation—the erroneous incorporation of amino acids into nascent proteins—is a source of protein variation that is orders of magnitude more frequent than DNA mutation. Like other sources of nongenetic variation, it can affect adaptive evolution. We study the evolutionary consequences of mistra...

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Detalles Bibliográficos
Autores principales: Schmutzer, Michael, Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280143/
https://www.ncbi.nlm.nih.gov/pubmed/37283551
http://dx.doi.org/10.1093/molbev/msad136