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Dihydroergotamine ameliorates liver fibrosis by targeting transforming growth factor β type II receptor

BACKGROUND: The transforming growth factor β (TGFβ) signaling pathway plays a crucial role in the development of liver fibrosis by activating TGFβ type II receptor (TGFβR2), followed by the recruitment of TGFβR1 finally triggering downstream signaling pathway. AIM: To find drugs targeting TGFβR2 tha...

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Detalles Bibliográficos
Autores principales: Zheng, Ke-Xin, Yuan, Shou-Li, Dong, Meng, Zhang, Han-Lin, Jiang, Xiao-Xiao, Yan, Chun-Long, Ye, Rong-Cai, Zhou, Hui-Qiao, Chen, Li, Jiang, Rui, Cheng, Zi-Yu, Zhang, Zhi, Wang, Qi, Jin, Wan-Zhu, Xie, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280794/
https://www.ncbi.nlm.nih.gov/pubmed/37346154
http://dx.doi.org/10.3748/wjg.v29.i20.3103