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Induction of filopodia formation by α-Actinin-2 via RelA with a feedforward activation loop promoting overt bone marrow metastasis of gastric cancer

BACKGROUND: Bone marrow metastasis (BMM) is underestimated in gastric cancer (GC). GC with BMM frequently complicate critical hematological abnormalities like diffused intravascular coagulation and microangiopathic hemolytic anemia, which constitute a highly aggressive GC (HAGC) subtype. HAGC presen...

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Detalles Bibliográficos
Autores principales: Wang, Caiqin, Xie, Bo, Yin, Shi, Cao, Jianghua, Huang, Junhao, Jin, Longyang, Du, Ge, Zhai, Xiaohui, Zhang, Rongqin, Li, Shanshan, Cao, Taiyuan, Yu, Hongen, Fan, Xinjuan, Yang, Zuli, Peng, Junsheng, Xiao, Jian, Lian, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280853/
https://www.ncbi.nlm.nih.gov/pubmed/37337244
http://dx.doi.org/10.1186/s12967-023-04156-w