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ERBB2-PTGS2 axis promotes intervertebral disc degeneration by regulating senescence of nucleus pulposus cells

Intervertebral disc degeneration (IDD) is considered one of the main causes of low back pain and lumbar disc herniation. Various studies have shown that disc cell senescence plays a critical role in this process. however, its role in IDD is yet unclear. In this study, we explored the role of senesce...

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Detalles Bibliográficos
Autores principales: Li, Zhao-Cheng., An, Fu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10280935/
https://www.ncbi.nlm.nih.gov/pubmed/37340393
http://dx.doi.org/10.1186/s12891-023-06625-1