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Recyclization of morpholinochromonylidene–thiazolidinone using nucleophiles: facile synthesis, cytotoxic evaluation, apoptosis, cell cycle and molecular docking studies of a novel series of azole, azine, azepine and pyran derivatives

A convenient synthetic approach for construction of a novel series of substituted azoles, azines, azepines and pyrans clubbed with a morpholinothiazolidinone hybrid was achieved. The methodology depended on ring-opening and ring-closure (RORC) of chromone ring in 2-(morpholinoimino)-5-[(4-oxo-4H-chr...

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Detalles Bibliográficos
Autores principales: Ali, Tarik E., Assiri, Mohammed A., Alqahtani, Maha N., Shati, Ali. A., Alfaifi, Mohammad. Y., Elbehairi, Serag. E. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281007/
https://www.ncbi.nlm.nih.gov/pubmed/37346943
http://dx.doi.org/10.1039/d3ra02777e