High-dimensional single-cell analysis unveils distinct immune signatures of peripheral blood in patients with pancreatic ductal adenocarcinoma

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies with poor response to immune checkpoint inhibitors. The mechanism of such poor response is not completely understood. METHODS: We assessed T-cell receptor (TCR) repertoire and RNA expression at the single-ce...

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Detalles Bibliográficos
Autores principales: Pan, Yu, Gao, Jianfeng, Lin, Jiajing, Ma, Yuan, Hou, Zelin, Lin, Yali, Wen, Shi, Pan, Minggui, Lu, Fengchun, Huang, Heguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281055/
https://www.ncbi.nlm.nih.gov/pubmed/37347110
http://dx.doi.org/10.3389/fendo.2023.1181538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281055/
https://www.ncbi.nlm.nih.gov/pubmed/37347110
http://dx.doi.org/10.3389/fendo.2023.1181538

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