Analysis of Structural Variants Previously Associated With ALS in Europeans Highlights Genomic Architectural Differences in Africans

BACKGROUND AND OBJECTIVES: Amyotrophic lateral sclerosis (ALS) is a degenerative condition of the brain and spinal cord in which protein-coding variants in known ALS disease genes explain a minority of sporadic cases. There is a growing interest in the role of noncoding structural variants (SVs) as...

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Detalles Bibliográficos
Autores principales: Monnakgotla, Nomakhosazana R., Mahungu, Amokelani C., Heckmann, Jeannine M., Botha, Gerrit, Mulder, Nicola J., Wu, Gang, Rampersaud, Evadnie, Myers, Jason, Van Blitterswijk, Marka, Rademakers, Rosa, Taylor, J. Paul, Wuu, Joanne, Benatar, Michael, Nel, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281237/
https://www.ncbi.nlm.nih.gov/pubmed/37346932
http://dx.doi.org/10.1212/NXG.0000000000200077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281237/
https://www.ncbi.nlm.nih.gov/pubmed/37346932
http://dx.doi.org/10.1212/NXG.0000000000200077

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