Effectiveness of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograft

This study exploited a novel patient-derived xenograft (PDX) of desmoplastic small round cell tumor (DSRCT), which reproduces histomorphological and molecular characteristics of the clinical tumor, to assess the activity of cytotoxic and targeted anticancer agents. Antitumor effect was moderate for...

Descripción completa

Detalles Bibliográficos
Autores principales: Zuco, Valentina, Pasquali, Sandro, Tortoreto, Monica, Percio, Stefano, Doldi, Valentina, Barisella, Marta, Collini, Paola, Dagrada, Gian Paolo, Brich, Silvia, Gasparini, Patrizia, Fiore, Marco, Casanova, Michela, Frezza, Anna Maria, Gronchi, Alessandro, Stacchiotti, Silvia, Ferrari, Andrea, Zaffaroni, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281256/
https://www.ncbi.nlm.nih.gov/pubmed/37158111
http://dx.doi.org/10.1242/dmm.049649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281256/
https://www.ncbi.nlm.nih.gov/pubmed/37158111
http://dx.doi.org/10.1242/dmm.049649

Ejemplares similares