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Effectiveness of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograft
This study exploited a novel patient-derived xenograft (PDX) of desmoplastic small round cell tumor (DSRCT), which reproduces histomorphological and molecular characteristics of the clinical tumor, to assess the activity of cytotoxic and targeted anticancer agents. Antitumor effect was moderate for...
Autores principales: | Zuco, Valentina, Pasquali, Sandro, Tortoreto, Monica, Percio, Stefano, Doldi, Valentina, Barisella, Marta, Collini, Paola, Dagrada, Gian Paolo, Brich, Silvia, Gasparini, Patrizia, Fiore, Marco, Casanova, Michela, Frezza, Anna Maria, Gronchi, Alessandro, Stacchiotti, Silvia, Ferrari, Andrea, Zaffaroni, Nadia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281256/ https://www.ncbi.nlm.nih.gov/pubmed/37158111 http://dx.doi.org/10.1242/dmm.049649 |
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