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Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets

Lipid droplets (LDs), crucial regulators of lipid metabolism, accumulate during oocyte development. However, their roles in fertility remain largely unknown. During Drosophila oogenesis, LD accumulation coincides with the actin remodeling necessary for follicle development. Loss of the LD-associated...

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Detalles Bibliográficos
Autores principales: Giedt, Michelle S., Thomalla, Jonathon M., White, Roger P., Johnson, Matthew R., Lai, Zon Weng, Tootle, Tina L., Welte, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281261/
https://www.ncbi.nlm.nih.gov/pubmed/37306387
http://dx.doi.org/10.1242/dev.201516