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Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets
Lipid droplets (LDs), crucial regulators of lipid metabolism, accumulate during oocyte development. However, their roles in fertility remain largely unknown. During Drosophila oogenesis, LD accumulation coincides with the actin remodeling necessary for follicle development. Loss of the LD-associated...
Autores principales: | Giedt, Michelle S., Thomalla, Jonathon M., White, Roger P., Johnson, Matthew R., Lai, Zon Weng, Tootle, Tina L., Welte, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281261/ https://www.ncbi.nlm.nih.gov/pubmed/37306387 http://dx.doi.org/10.1242/dev.201516 |
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