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Vinculin Y822 is an important determinant of ligand binding

Vinculin is an actin-binding protein present at cell–matrix and cell–cell adhesions, which plays a critical role in bearing force experienced by cells and dissipating it onto the cytoskeleton. Recently, we identified a key tyrosine residue, Y822, whose phosphorylation plays a critical role in force...

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Detalles Bibliográficos
Autores principales: DeWane, Gillian, Cronin, Nicholas M., Dawson, Logan W., Heidema, Christy, DeMali, Kris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281268/
https://www.ncbi.nlm.nih.gov/pubmed/37248996
http://dx.doi.org/10.1242/jcs.260104