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Vinculin Y822 is an important determinant of ligand binding
Vinculin is an actin-binding protein present at cell–matrix and cell–cell adhesions, which plays a critical role in bearing force experienced by cells and dissipating it onto the cytoskeleton. Recently, we identified a key tyrosine residue, Y822, whose phosphorylation plays a critical role in force...
Autores principales: | DeWane, Gillian, Cronin, Nicholas M., Dawson, Logan W., Heidema, Christy, DeMali, Kris A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281268/ https://www.ncbi.nlm.nih.gov/pubmed/37248996 http://dx.doi.org/10.1242/jcs.260104 |
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