Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB

In this study, based on the effect of compounds on the activation of NF-κB and NO release, compound 51 was discovered as the best one with NO release inhibition IC(50) value was 3.1 ± 1.1 μM and NF-κB activity inhibition IC(50) value was 172.2 ± 11.4 nM. Compound 51 could inhibit the activation of N...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Yaoyao, Lv, Qi, Zhou, Feilong, Jian, Yujie, Xinhua, Liu, Chen, Xing, Hu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281321/
https://www.ncbi.nlm.nih.gov/pubmed/37325874
http://dx.doi.org/10.1080/14756366.2023.2225135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281321/
https://www.ncbi.nlm.nih.gov/pubmed/37325874
http://dx.doi.org/10.1080/14756366.2023.2225135

Ejemplares similares