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Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB
In this study, based on the effect of compounds on the activation of NF-κB and NO release, compound 51 was discovered as the best one with NO release inhibition IC(50) value was 3.1 ± 1.1 μM and NF-κB activity inhibition IC(50) value was 172.2 ± 11.4 nM. Compound 51 could inhibit the activation of N...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281321/ https://www.ncbi.nlm.nih.gov/pubmed/37325874 http://dx.doi.org/10.1080/14756366.2023.2225135 |