PEGylated pH-responsive peptide-mRNA nano self-assemblies enhance the pulmonary delivery efficiency and safety of aerosolized mRNA

Inhalable messenger RNA (mRNA) has demonstrated great potential in therapy and vaccine development to confront various lung diseases. However, few gene vectors could overcome the airway mucus and intracellular barriers for successful pulmonary mRNA delivery. Apart from the low pulmonary gene deliver...

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Detalles Bibliográficos
Autores principales: Xu, Yingying, Zheng, Yijing, Ding, Xuqiu, Wang, Chengyan, Hua, Bin, Hong, Shilian, Huang, Xiaoman, Lin, Jiali, Zhang, Peng, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281356/
https://www.ncbi.nlm.nih.gov/pubmed/37336779
http://dx.doi.org/10.1080/10717544.2023.2219870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281356/
https://www.ncbi.nlm.nih.gov/pubmed/37336779
http://dx.doi.org/10.1080/10717544.2023.2219870

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