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Evidence-based Medicine and Mechanistic Evidence: The Case of the Failed Rollout of Efavirenz in Zimbabwe

Evidence-based medicine (EBM) has long deemphasized mechanistic reasoning and pathophysiological rationale in assessing the effectiveness of interventions. The EBM+ movement has challenged this stance, arguing that evidence of mechanisms and comparative studies should both be seen as necessary and c...

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Detalles Bibliográficos
Autores principales: Park, Andrew, Steel, Daniel, Maine, Elicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281362/
https://www.ncbi.nlm.nih.gov/pubmed/37137159
http://dx.doi.org/10.1093/jmp/jhad019