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RTK signalling promotes epithelial columnar cell shape and apical junction maintenance in human lung progenitor cells
Multipotent epithelial progenitor cells can be expanded from human embryonic lungs as organoids and maintained in a self-renewing state using a defined medium. The organoid cells are columnar, resembling the cell morphology of the developing lung tip epithelium in vivo. Cell shape dynamics and fate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281517/ https://www.ncbi.nlm.nih.gov/pubmed/37260147 http://dx.doi.org/10.1242/dev.201284 |