The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability

Restricting the localization of the evolutionarily conserved centromeric histone H3 variant CENP-A to centromeres prevents chromosomal instability (CIN). The mislocalization of CENP-A to non-centromeric regions contributes to CIN in yeasts, flies and human cells. Even though overexpression and mislo...

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Detalles Bibliográficos
Autores principales: Shrestha, Roshan L., Balachandra, Vinutha, Kim, Jee Hun, Rossi, Austin, Vadlamani, Pranathi, Sethi, Subhash Chandra, Ozbun, Laurent, Lin, Shinjen, Cheng, Ken Chin-Chien, Chari, Raj, Karpova, Tatiana S., Pegoraro, Gianluca, Foltz, Daniel R., Caplen, Natasha J., Basrai, Munira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281518/
https://www.ncbi.nlm.nih.gov/pubmed/37129573
http://dx.doi.org/10.1242/jcs.260944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281518/
https://www.ncbi.nlm.nih.gov/pubmed/37129573
http://dx.doi.org/10.1242/jcs.260944

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