A dynamical systems treatment of transcriptomic trajectories in hematopoiesis

Inspired by Waddington's illustration of an epigenetic landscape, cell-fate transitions have been envisioned as bifurcating dynamical systems, wherein exogenous signaling dynamics couple to the enormously complex signaling and transcriptional machinery of a cell to elicit qualitative transition...

Descripción completa

Detalles Bibliográficos
Autores principales: Freedman, Simon L., Xu, Bingxian, Goyal, Sidhartha, Mani, Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281553/
https://www.ncbi.nlm.nih.gov/pubmed/37260149
http://dx.doi.org/10.1242/dev.201280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281553/
https://www.ncbi.nlm.nih.gov/pubmed/37260149
http://dx.doi.org/10.1242/dev.201280

Ejemplares similares