Dual CSF1R inhibition and CD40 activation demonstrates anti-tumor activity in a 3D macrophage- HER2(+) breast cancer spheroid model

The complex interaction between tumor-associated macrophages (TAMs) and tumor cells through soluble factors provides essential cues for breast cancer progression. TAMs-targeted therapies have shown promising clinical therapeutical potential against cancer progression. The molecular mechanisms underl...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodriguez-Perdigon, Manuel, Haeni, Laetitia, Rothen-Rutishauser, Barbara, Rüegg, Curzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281737/
https://www.ncbi.nlm.nih.gov/pubmed/37346794
http://dx.doi.org/10.3389/fbioe.2023.1159819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281737/
https://www.ncbi.nlm.nih.gov/pubmed/37346794
http://dx.doi.org/10.3389/fbioe.2023.1159819

Ejemplares similares