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Dual CSF1R inhibition and CD40 activation demonstrates anti-tumor activity in a 3D macrophage- HER2(+) breast cancer spheroid model

The complex interaction between tumor-associated macrophages (TAMs) and tumor cells through soluble factors provides essential cues for breast cancer progression. TAMs-targeted therapies have shown promising clinical therapeutical potential against cancer progression. The molecular mechanisms underl...

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Detalles Bibliográficos
Autores principales:	Rodriguez-Perdigon, Manuel, Haeni, Laetitia, Rothen-Rutishauser, Barbara, Rüegg, Curzio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281737/ https://www.ncbi.nlm.nih.gov/pubmed/37346794 http://dx.doi.org/10.3389/fbioe.2023.1159819

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