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Activation of Kir2.1 improves myocardial fibrosis by inhibiting Ca (2+) overload and the TGF-β1/Smad signaling pathway : Activation of Kir2.1 improves myocardial fibrosis

The inwardly rectifying potassium channel Kir2.1 is closely associated with many cardiovascular diseases. However, the effect and mechanism of Kir2.1 in diabetic cardiomyopathy remain unclear. In vivo, we use STZ to establish the model, and ventricular structural changes, myocardial inflammatory inf...

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Detalles Bibliográficos
Autores principales: Rong, Yi, Zhou, Xin, Guo, Zhenli, Zhang, Yingying, Qin, Wenjuan, Li, Li, Si, Junqiang, Yang, Rui, Li, Xinzhi, Ma, Ketao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281881/
https://www.ncbi.nlm.nih.gov/pubmed/37184279
http://dx.doi.org/10.3724/abbs.2023083